Publications 2018

Madrahimov N, Khalikov A, Boyle EC, Natanov R, Knoefel A-K, Siemeni T, Hoeffler K, Haverich A, Maus U, Kuehn C. Veno-venous extracorporeal membrane oxygenation in a mouse. JoVE. 2018:e58146. https://www.jove.com/video/58146

Bengel FM, Ross TL. Emerging imaging targets for infiltrative cardiomyopathy: Inflammation and fibrosis. J Nucl Cardiol. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29968156

Chatterjee S, de Gonzalo-Calvo D, Derda AA, Schimmel K, Sonnenschein K, Bavendiek U, Bauersachs J, Bar C, Thum T. Leukocyte telomere length correlates with hypertrophic cardiomyopathy severity. Sci Rep. 2018; 8:11227-018-29072-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060137/

de Gonzalo-Calvo D, Cediel G, Bar C, Nunez J, Revuelta-Lopez E, Gavara J, Rios-Navarro C, Llorente-Cortes V, Bodi V, Thum T, Bayes-Genis A. Circulating miR-1254 predicts ventricular remodeling in patients with ST-segment-elevation myocardial infarction: A cardiovascular magnetic resonance study. Sci Rep. 2018; 8:15115-018-33491-y. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181905/

Derda AA, Pfanne A, Bar C, Schimmel K, Kennel PJ, Xiao K, Schulze PC, Bauersachs J, Thum T. Blood-based microRNA profiling in patients with cardiac amyloidosis. PLoS One. 2018; 13:e0204235. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192556/

Koch L, Deiwick A, Franke A, Schwanke K, Haverich A, Zweigerdt R, Chichkov B. Laser bioprinting of human induced pluripotent stem cells-the effect of printing and biomaterials on cell survival, pluripotency, and differentiation. Biofabrication. 2018; 10:035005-5090/aab981. https://www.ncbi.nlm.nih.gov/pubmed/29578448

Maack C, Eschenhagen T, Hamdani N, Heinzel FR, Lyon AR, Manstein DJ, Metzger J, Papp Z, Tocchetti CG, Yilmaz MB, Anker SD, Balligand JL, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland JG, de Boer RA, Dietl A, Fischmeister R, Harjola VP, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke WA, Lund LH, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristic A, Ruschitzka F, Seferovic PM, Skouri H, Zimmermann WH, Mebazaa A. Treatments targeting inotropy. Eur Heart J. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30295807

Madrahimov N, Boyle EC, Gueler F, Goecke T, Knofel AK, Irkha V, Maegel L, Hoffler K, Natanov R, Ismail I, Maus U, Kuhn C, Warnecke G, Shrestha ML, Cebotari S, Haverich A. Novel mouse model of cardiopulmonary bypass. Eur J Cardiothorac Surg. 2018; 53:186-193. https://www.ncbi.nlm.nih.gov/pubmed/28977367

Michels G, Wengenmayer T, Hagl C, Dohmen C, Böttiger BW, Bauersachs J, Markewitz A, Bauer A, Gräsner J-, Pfister R, Ghanem A, Busch H-, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H. Empfehlungen zur extrakorporalen kardiopulmonalen reanimation (eCPR). Medizinische Klinik - Intensivmedizin und Notfallmedizin. 2018; 113:478-486. https://doi.org/10.1007/s00063-018-0452-8

Michels G, Wengenmayer T, Hagl C, Dohmen C, Bottiger BW, Bauersachs J, Markewitz A, Bauer A, Grasner JT, Pfister R, Ghanem A, Busch HJ, Kreimeier U, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R, Thiele H. Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR): Consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC. Clin Res Cardiol. 2018. https://www.ncbi.nlm.nih.gov/pubmed/30361819

Natanov R, Gueler F, Falk CS, Kuhn C, Maus U, Boyle EC, Siemeni T, Knoefel AK, Cebotari S, Haverich A, Madrahimov N. Blood cytokine expression correlates with early multi-organ damage in a mouse model of moderate hypothermia with circulatory arrest using cardiopulmonary bypass. PLoS One. 2018; 13:e0205437. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181365/

Olmer R, Engels L, Usman A, Menke S, Malik MNH, Pessler F, Gohring G, Bornhorst D, Bolten S, Abdelilah-Seyfried S, Scheper T, Kempf H, Zweigerdt R, Martin U. Differentiation of human pluripotent stem cells into functional endothelial cells in scalable suspension culture. Stem Cell Reports. 2018; 10:1657-1672. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995343/

Wolling H, Konze SA, Hofer A, Erdmann J, Pich A, Zweigerdt R, Buettner FFR. Quantitative secretomics reveals extrinsic signals involved in human pluripotent stem cell cardiomyogenesis. Proteomics. 2018; 18:e1800102. https://www.ncbi.nlm.nih.gov/pubmed/?term=29905012

Wert L, Hanke JS, Dogan G, Ricklefs M, Fleissner F, Chatterjee A, Feldmann C, Haverich A, Schmitto JD. Reduction of driveline infections through doubled driveline tunneling of left ventricular assist devices-5-year follow-up. J Thorac Dis. 2018; 10:S1703-S1710. www.ncbi.nlm.nih.gov/pubmed/30034842

Dogan G, Hanke JS, Ricklefs M, Chatterjee A, Feldmann C, Mashaqi B, Deniz E, Haverich A, Schmitto JD. MitraClip procedure prior to left ventricular assist device implantation. J Thorac Dis. 2018; 10:S1763-S1768. www.ncbi.nlm.nih.gov/pubmed/30034850

Ricklefs M, Hanke JS, Dogan G, Chatterjee A, Feldmann C, Deniz E, Korte W, Kirchhoff F, Haverich A, Schmitto JD. Successful HeartMate 3 implantation in isolated right heart failure-first in man experience of right heart configuration. J Thorac Dis. 2018; 10:S1834-S1837. www.ncbi.nlm.nih.gov/pubmed/ 30034861

Grund A, Szaroszyk M, Doppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Muller OJ, Bauersachs J, Heineke J. A gene therapeutic approach to inhibit CIB1 ameliorates maladaptive remodeling in pressure overload. Cardiovasc Res. 2018. www.ncbi.nlm.nih.gov/pubmed/29931050

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J. Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice. J Mol Cell Cardiol. 2018. www.ncbi.nlm.nih.gov/pubmed/30118791

Bauersachs J, Heymans S. Scientific updates on the interaction of genes, epigenetics and multi-cellularity in cardiovascular diseases, the working group of myocardial function of the ESC. Cardiovasc Res. 2018. www.ncbi.nlm.nih.gov/pubmed/29992298

Sieweke JT, Pfeffer TJ, Berliner D, Konig T, Hallbaum M, Napp LC, Tongers J, Kuhn C, Schmitto JD, Hilfiker-Kleiner D, Schafer A, Bauersachs J. Cardiogenic shock complicating peripartum cardiomyopathy: Importance of early left ventricular unloading and bromocriptine therapy. Eur Heart J Acute Cardiovasc Care. 2018: 2048872618777876. www.ncbi.nlm.nih.gov/pubmed/29792513

Crespo-Leiro MG, Metra M, Lund LH, Milicic D, Costanzo MR, Filippatos G, Gustafsson F, Tsui S, Barge-Caballero E, De Jonge N, Frigerio M, Hamdan R, Hasin T, Hulsmann M, Nalbantgil S, Potena L, Bauersachs J, Gkouziouta A, Ruhparwar A, Ristic AD, Straburzynska-Migaj E, McDonagh T, Seferovic P, Ruschitzka F. Advanced heart failure: A position statement of the heart failure association of the european society of cardiology. Eur J Heart Fail. 2018. www.ncbi.nlm.nih.gov/pubmed/ 29806100

Koestenberger M, Avian A, Cantinotti M, Hansmann G, for the European Pediatric Pulmonary Vascular Disease Network. Tricuspid annular plane systolic excursion (TAPSE) in pediatric pulmonary hypertension: integrating right ventricular ejection efficiency (RVEe) into advanced multi-parametric imaging. International Journal of Cardiology. 2018 (in press).

Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis SA, Rog-Zielinska EA, Kourembanas S, Jonigk D, Hansmann G. PPARgamma agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation. Sci Transl Med. 2018; 10:10.1126/scitranslmed.aao0303. www.ncbi.nlm.nih.gov/pubmed/29695452

Koestenberger M, Avian A, Gamillscheg A, Sallmon H, Grangl G, Burmas A, Schweintzger S, Kurath-Koller S, Cvirn G, Hansmann G. Right ventricular base/apex ratio in the assessment of pediatric pulmonary arterial hypertension - results from the european pediatric pulmonary vascular disease network. Clin Cardiol. 2018. www.ncbi.nlm.nih.gov/pubmed/ 29896859

Thackeray JT, Hupe HC, Wang Y, Bankstahl JP, Berding G, Ross TL, Bauersachs J, Wollert KC, Bengel FM. Myocardial inflammation predicts remodeling and neuroinflammation after myocardial infarction. J Am Coll Cardiol. 2018; 71:263-275. www.ncbi.nlm.nih.gov/pubmed/29348018

Sieweke JT, Berliner D, Tongers J, Napp LC, Flierl U, Zauner F, Bauersachs J, Schafer A. Mortality in patients with cardiogenic shock treated with the Impella CP microaxial pump for isolated left ventricular failure. Eur Heart J Acute Cardiovasc Care. 2018; 2048872618757393. www.ncbi.nlm.nih.gov/pubmed/29405734

Koestenberger M, Avian A, Sallmon H, Gamillscheg A, Grangl G, Kurath-Koller S, Schweintzger S, Burmas A, Hansmann G. The right ventricular outflow tract in pediatric pulmonary hypertension-data from the european pediatric pulmonary vascular disease network. Echocardiography. 2018; 35:841-848. www.ncbi.nlm.nih.gov/pubmed/29505663

Hanke JS, Dogan G, Zoch A, Ricklefs M, Wert L, Feldmann C, Bara C, Shrestha M, Tillmanns J, Kempf T, Bauersachs J, Haverich A, Schmitto JD. One-year outcomes with the HeartMate 3 left ventricular assist device. J Thorac Cardiovasc Surg. 2018; 156:662-669.  www.ncbi.nlm.nih.gov/pubmed/29525258

2017

Madrahimov N, Natanov R, Boyle EC, Goecke T, Knofel AK, Irkha V, Solovieva A, Hoffler K, Maus U, Kuhn C, Ismail I, Warnecke G, Shrestha ML, Cebotari S, Haverich A. Cardiopulmonary bypass in a mouse model: A novel approach. J Vis Exp. 2017;(127). https://www.ncbi.nlm.nih.gov/pubmed/28994765

Napp LC, Vogel-Claussen J, Schafer A, Haverich A, Bauersachs J, Kuhn C, Tongers J. First-in-Man Fully Percutaneous Complete Bypass of Heart and Lung. JACC Cardiovasc Interv. 2017; 10: e231-e233. www.ncbi.nlm.nih.gov/pubmed/29198456

Flierl U, Tongers J, Berliner D, Sieweke JT, Zauner F, Wingert C, Riehle C, Bauersachs J, Schafer A. Acquired von Willebrand syndrome in cardiogenic shock patients on mechanical circulatory microaxial pump support. PLoS One. 2017; 12: e0183193. www.ncbi.nlm.nih.gov/pubmed/28806755

Hartung D, Hueper K, Chen R, Gutberlet M, Wacker F, Meier M, Rong S, Jang MS, Brasen JH, Gueler F. T2 Mapping for Noninvasive Assessment of Interstitial Edema in Acute Cardiac Allograft Rejection in a Mouse Model of Heterotopic Heart Transplantation. Invest Radiol. 2017; 53:271-277. www.ncbi.nlm.nih.gov/pubmed/29261532

Thackeray JT, Pietzsch S, Stapel B, Ricke-Hoch M, Lee CW, Bankstahl JP, Scherr M, Heineke J, Scharf G, Haghikia A, Bengel FM, Hilfiker-Kleiner D. Insulin supplementation attenuates cancer-induced cardiomyopathy and slows tumor disease progression. JCI Insight. 2017; 2: 10.1172/jci.insight.93098. www.ncbi.nlm.nih.gov/pubmed/28515362

Hansmann G. Pulmonary hypertension in infants, children, and young adults. J Am Coll Cardiol. 2017; 69:2551-2569. www.ncbi.nlm.nih.gov/pubmed/28521893